BOSTON, Oct. 02, 2023 (GLOBE NEWSWIRE) — Praxis Precision Medicines, Inc. (NASDAQ: PRAX), a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance, today provided an update on its clinical portfolio at the company’s R&D Day. Praxis’ leaders were joined by two esteemed […]
June 15, 2023 – By Gina Shaw, Neurology Today The incidence of Parkinson’s disease (PD) in patients with essential tremor (ET) is significantly higher than that reported in historical population-based control groups across numerous countries, according to a prospective longitudinal study published online May 10 in Neurology: Clinical Practice. The findings are consistent with those of […]
By Tish Hevel, CEOBrain Donor Project If you’re interested in advancing the science of neurologic diseases and disorders, including essential tremor, here’s something you may want to consider: making arrangements now to donate your brain when you die. There is currently an urgent need for brain donation for a variety of neurological disorders. Breakthroughs in […]
Elan D. Louis, MD, MS,Department of Neurology, University of TexasSouthwestern Medical Center,Dallas, Texas One question my patients with essential tremor (ET) often ask me is “how common is essential tremor?” Knowing the answer to this question is important because it helps patients place what they are experiencing into some sort of larger context. To answer […]
DUBLIN, Dec. 15, 2021 /PRNewswire/ — Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced that the first patient has been enrolled in a global Phase 2b clinical trial evaluating the safety and efficacy of suvecaltamide (also known as JZP385), a highly selective modulator of T-type calcium channels in development for the potential treatment of moderate to severe essential tremor (ET).1 The multicenter, double-blind, […]
September 2021 – Recent gifts from generous donors have provided the International Essential Tremor Foundation with the opportunity to revamp its 20-year-old research grant program for a more meaningful and long-term impact. When the grant program was established in 2001, it entailed awarded up to two $25,000 grants per year to studies addressing the nosology, […]
By Jean P. Hubble, M.D. The diagnosis is usually quite obvious – rhythmic shaking of the hands. Despite the fact that essential tremor (ET) is common and easily recognized, there are many aspects about the clinical presentation which are poorly understood. Virtually all individuals with ET have tremor of the hands. The next most frequently […]
(Nature Neuroscience, March 18, 2021) Cannabinoids reduce tremor associated with motor disorders induced by injuries and neurodegenerative disease. Here we show that this effect is mediated by cannabinoid receptors on astrocytes in the ventral horn of the spinal cord, where alternating limb movements are initiated. We first demonstrate that tremor is reduced in a mouse […]
Clinical trials can be confusing. Amber Trzeciak, with Cadent Therapeutics, explains how they work and why they are important for the development of new drugs and treatments for medical conditions like essential tremor.
By Jean P. Hubble, MD The diagnosis is usually quite obvious – rhythmic shaking of the hands. Despite the fact that essential tremor (ET) is common and easily recognized, there are many aspects about the clinical presentation which are poorly understood. Virtually all individuals with ET have tremor of the hands. The next most frequently […]