(Nature Neuroscience, March 18, 2021) Cannabinoids reduce tremor associated with motor disorders induced by injuries and neurodegenerative disease. Here we show that this effect is mediated by cannabinoid receptors on astrocytes in the ventral horn of the spinal cord, where alternating limb movements are initiated. We first demonstrate that tremor is reduced in a mouse […]
Clinical trials can be confusing. Amber Trzeciak, with Cadent Therapeutics, explains how they work and why they are important for the development of new drugs and treatments for medical conditions like essential tremor.
By Jean P. Hubble, MD The diagnosis is usually quite obvious – rhythmic shaking of the hands. Despite the fact that essential tremor (ET) is common and easily recognized, there are many aspects about the clinical presentation which are poorly understood. Virtually all individuals with ET have tremor of the hands. The next most frequently […]
Patient recruitment is usually the biggest challenge in conducting clinical trials. Thanks to the International Essential Tremor Foundation and their members, Cala Health recently enrolled the largest therapeutic essential tremor study in record time. By Kate Rosenbluth,Founder/CEO of Cala Health, Inc. About five years ago, my co-founders and I spun Cala Health out from Stanford […]
We sometimes take for granted the vast history of medical research and its impact on human ailments and diseases. Most people have heard of polio and tuberculosis, which today are easily preventable with a vaccine. Organ transplants extend life for many and the pacemaker regulates the heart’s rhythm for people with irregular heartbeats. Physicians can […]